Study of Complications of Transarterial Chemoembolization for Huge Hepatocellular Carcinoma

Ze Song, Yinfeng Xu, Zhongxin Luo, Jiaping Li and Yingqiang Zhang

Department of Oncology, The Seventh Affiliated Hospital, Sun Yat-sen University, China Department of Hand Surgery and Microsurgery, The First Affiliated Hospital, Sun Yat-sen University, China Department of Radiology, The Seventh Affiliated Hospital, Sun Yat-sen University, China Department of Interventional Oncology, The First Affiliated Hospital, Sun Yat-sen University, China Department of Interventional Radiology, The Seventh Affiliated Hospital, Sun Yat-sen University, China

^*Correspondance to: Yingqiang Zhang 

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Abstract:

Objective: To study the complications of Transarterial Chemoembolization (TACE) for Huge Hepatocellular Carcinoma (HCC). Methods: Between July 2013 and December 2016, Ninety-eight patients with huge HCC (>10 cm in diameter) treated with TACE were reviewed. Complications related to TACE were recorded based on Electronic Medical Record (EMR). Results: A total of 245 TACE procedures were performed. The mean number of TACE sessions was 3.2 ± 1.5 (range 1-6). Twenty-four of 98 patients experienced complications and the morbidity rate was 24.5%. Eight patients died from TACE-related complications within one month, the mortality rate was 8.2%. The most common complications were hepatic insufficiency, and the morbidity was 9.4%. The other complications consist of spontaneous tumor rupture, liver abscess, pulmonary embolism, cholecystitis, hepatic artery injuries, gastrointestinal bleeding. Conclusion: Although the severe complications of TACE for huge HCC are rare, cautiously performing the procedure and selecting appropriate candidate is necessary.

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Cite the Article:

Song Z, Xu Y, Luo Z, Li J, Zhang Y. Study of Complications of Transarterial Chemoembolization for Huge Hepatocellular Carcinoma. World J Surg Surgical Res. 2019; 2: 1159..