Correlation Analysis between Cervical Refractory Ureaplasma urealyticum Infection and IVF Pregnancy Outcome

Ling-Nv Yao, Nan Jiang, Chuyan Li, Jing Chen and Wen-Qin Lin*

Reproductive Medical Center, First Affiliated Hospital, School of Medicine, Zhejiang University, China

^*Correspondance to: JianWen-Qin Lin 

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Abstract:

Objectives: To determine the effect of cervical refractory Ureaplasma urealyticum infection on assisted reproductive outcomes. Patients and Methods: A total of 273 patients who received In Vitro Fertilization (IVF) treatment were included in this study. The ages of the female patients ranged from 20 to 35 years. All patients have normal ovarian reserve (AFC ≥ 7) and regular menstruation and were divided into Group 1 (UU–, 151 patients), Group 2 (Patients who turned negative after UU treatment, 52 patients) and Group 3 (UU after 3 cycles of sensitive antibiotic treatment has not turned negative, 70 patients). Results: The positive rate of Ureaplasma urealyticum in these patients was 44.7% (122/273). The rate of negative conversion of Ureaplasma urealyticum positive patients after 1 to 3 time's sensitive antibiotic treatment was 42.6% (52/122). There were no significantly difference of number of eggs obtained, number of fertilizations, rate of high-quality embryos and blastocyst formation rate among the three groups. And there were no significant differences in the clinical pregnancy rates, biochemical pregnancy rates, embryo implantation rates, spontaneous abortion rates, ectopic pregnancy rates, fetal malformation rates, live birth rates, even pre-birth rate. Conclusion: Though the positive rate of Ureaplasma urealyticum infection in women of childbearing age is high, there is no need for routine screening of Ureaplasma urealyticum in assisted reproductive women.

Keywords:

Ureaplasma urealyticum infection; IVF; Pregnancy outcome; Infertility

Cite the Article:

Yao L-N, Jiang N, Li C, Chen J, Lin W-Q. Correlation Analysis between Cervical Refractory Ureaplasma urealyticum Infection and IVF Pregnancy Outcome. World J Surg Surgical Res. 2022; 5: 1365..