Prevalence of Virulence Genes in Acinetobacter baumannii Isolated from Clinical Samples in Mymensingh Medical College Hospital

Ara H

Department of Microbiology, Mymensingh Medical College, Bangladesh

^*Correspondance to: Hosne Ara 

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Abstract:

Acinetobacter baumannii is an opportunistic bacterial pathogen that is the most important cause of hospital-acquired infections. The objective of this study was to evaluate the predominance and determination of virulence encoding genes in A. baumannii isolates. During study period from February 2019 to March 2020 of 380 clinical samples including endotracheal aspirates (70), wound swab/pus (175), urine (70) and blood (65) analyzed in inpatients admitted to the hospital in different unit like ICU, Surgery and Burn unit of Mymensingh Medical College Hospital. Out of 380 studied samples, 130 (34.21%) strains were yielded growth. Among 130 isolates, Acinetobacter spp. were 49 (37.69%). Totally, 39 (79.59%) were Acinetobacter baumannii which was detected by molecular technique PCR. Furthermore, the determination of virulence genes csgA and fimH detected by PCR. Among two studied virulence genes, csgA (38.46%) was the most prevalent virulent genes associated with disease severity and co-morbidity of the patient in A. baumannii infections.

Keywords:

Acinetobacter baumannii; Virulence genes; Bacterial pathogen

Cite the Article:

Ara H. Prevalence of Virulence Genes in Acinetobacter baumannii Isolated from Clinical Samples in Mymensingh Medical College Hospital. World J Surg Surgical Res. 2022; 5: 1429..